摘要
Abstract
Objective To observe the clinical efficacy of patients with neonatal jaundice treated by live combined clostridium butyricum and bifidobacterium powders(Chang Lekang) combined with blue-ray irradiation. Methods One hundred and fourteen patients diagnosed neonatal jaundice were randomly divided into single blue-ray irradiation treatment group(the blue-ray group), single Chang Lekang treatment group(the Chang Lekang group) and Chang Lekang combined with blue-ray irradiation treatment group(the unite group), every group had 38 cases, the course of the treatment was 5-7 days. The clinical symptoms change and serum total bilirubin(Tbil) change among the three groups were observed. Results There was not statistically significant difference in serum Tbil among the three groups before treatment(all P > 0.05); The serum Tbil of every group decreased after treatment and the difference was not statistically significant in the serum Tbil after 5 days' treatment between the blue-ray group and the Chang Lekang group[(182.45±18.56)vs(183.45±18.65),t=-0.948,P>0.05], while the difference was statistically significant in the serum Tbil between the unite group and the blue-ray group and between the unite group and the Chang Lekang group [(156.34±14.78)vs(182.45±18.56),(156.34±14.78)vs(183.45±18.65),the t-value was 6.324 and 7.226 respectively,both P < 0.05]. The days of serum Tbil dropped to normal in the unite group(3.86±1.33)was shorter than that in the blue-ray group(5.82±1.65)and the Chang Lekang group(5.78±1.62), and the differences were statistically significant(the t-value was 9.107 and 8.924 respectively,both P < 0.05). The total effective rate of the unite group after treatment was apparently higher than that of the blue-ray group and the Chang Lekang group, and the differences were statistically significant(94.74% vs 71.05%,94.74% vs 73.68%,x2=11.586,P=0.021). Conclusion The clinical effect of patients with neonatal jaundice treated by live combined clostridium butyricum and bifidobacterium powders combined with blue-ray irradiation is better than that of single blue-ray irradiation treatment, and it is worthy of popularization and application.关键词
新生儿黄疸/酪酸梭菌/双歧杆菌二联活菌散/蓝光Key words
Neonatal jaundice/Live combined clostridium butyricum and bifidobacterium powders/Blue-ray分类
医药卫生