摘要
Abstract
Objective To discuss the clinical effect of alprostadil on pulmonary hypertensio of newborn. Methods 200 cases of neonatal pulmonary hypertension patients who were admitted into our hospital were randomly divided into control group (100 cases) and treatment group (100 cases). The control group was treated with normal frequency ventilation, based on the normal frequency ventilation, the treatment group was treated with alprostadil. Compare and analysis the clinical efficacy, blood gas parameters, pressure of pulmonary artery systolic and ventilation time. Results After treatment, these parameters relevant with pulmonary hypertension such as pH, PaO2, PaCO2, SaO2, PASP in treatment group were significantly high than those in control group, and there was a significant difference between the two groups (P<0.05). The Ventilator was used in treatment group just for (84.5±3.7)h, which was significantly shorter than that in control group (150.3±6.6)h.In addition, the total efficiency of treatment group was 99.0%which significantly higher than that in control group (88.0%), the difference had statistically significant( P<0.05). Conclusion Alprostadil has high clinical effective on the treatment of pulmonary hypertension of newborns and has the value of promotion.关键词
前列地尔/肺动脉高压/新生儿/临床疗效Key words
Alprostadil/Pulmonary hypertension/Newborn/Clinical efficacy分类
医药卫生
