中国医药科学Issue(24)：86-87,2.
消旋卡多曲治疗小儿轮状病毒性肠炎的临床研究
Clinical research of racecadotril in treatment for rotavirus enteritis in children
郑健荣 1刘一鸣 2谭本仁3
作者信息
- 1. 韶关药业有限责任公司，广东韶关512026
- 2. 广东省韶关市妇幼保健院，广东韶关512026
- 3. 广东省韶关市粤北人民医院，广东韶关512026
- 折叠
摘要
Abstract
Objective To investigate the clinical effect of racecadotril in treatment for rotavirus enteritis in children. Methods 96 patients with rotavirus enteritis were selected in hospital, who were randomly divided into two groups. 48 patients treated ribavirin as control group. 48 patients treated racecadotril as observation group. Symptoms improvement situation, clinical efficacy, adverse reactions were compared between two groups. Results Antiemetic time(2.1±0.7)d; antidiarrheal time(2.5±0.9)d; cooling time(1.8±0.6) d; hospitalization time(4.6±1.3)d in observation group were significantly less than control group(2.6±1.0)d, (3.2±1.1)d, (2.3±0.8)d, (6.7±1.5)d. Total effective rate in observation group(97.9%) was significantly higher than control group(85.4%).Incidence of adverse reactions in observation group(4.2%) was significantly lower than control group(16.7%). Differences were statistically significant(P<0.05). Conclusion Racecadotril is an effective drug in treatment for rotavirus enteritis in children, which can significantly improve clinical symptoms and shorten treatment time.That has good clinical efficacy and high safety.关键词
消旋卡多曲/病毒唑/小儿轮状病毒性肠炎Key words
Racecadotril/Ribavirin/Rotavirus enteritis in children分类
医药卫生引用本文复制引用
郑健荣,刘一鸣,谭本仁..消旋卡多曲治疗小儿轮状病毒性肠炎的临床研究[J].中国医药科学,2013,(24):86-87,2.
