中国中西医结合外科杂志Issue(6):624-626,3.DOI:10.3969/j.issn.1007-6948.2013.06.004
肠脂肪酸结合蛋白和肌酸磷酸激酶在肠梗阻诊断中的意义
Diagnostic Value of Plasma Intestinal Fatty Acid-binding Protein and Creatine Kinase in Patients Sub-jected with Intestinal Obstruction
闫万里 1胡凯强2
作者信息
- 1. 河北省临西县第二人民医院普外科 临西 054901
- 2. 山西省儿童医院神经外科 太原 030013
- 折叠
摘要
Abstract
Objective To explore the diagnostic value of plasma intestinal fatty acid-binding protein (IF-ABP) and creatine kinase(CK) in patients with intestinal obstruction. Methods Twenty-seven patients subject-ed with intestinal obstruction were consecutively selected as observational group (OG), the 12 patients having en-terectomy were chosen as OG1, and the other 15 patients having celiotomy were chosen as OG2. Fifteen healthy adults were chosen as the control group(CG). Venous blood was collected from CG for once, and from OG on ad-mission, first and 3rd day after operation respectively. The concentrations of serum IFABP and CK were mea-sured. Results Compared with the patients in CG, the IFABP and CK levels in both OG were increased obvi-ously on admission(P<0.01), and were higher in the intestinal necrosis group(P<0.01). Subsequently, the IFABP levels decreased to normal on 1st day after op-eration in the patients in OGs, but the CK levels had no variance. The IFABP levels were no difference in the two OGs on 3rd day of postoperation,and the CK levels were lower than those before operation. Conclusion Serum IFABP and CK are sensitive markers to detect intestinal ischemia or necrosis and the IFABP has guided significance to the prognosis of intestinal obstruction in patients who subjected operation.关键词
肠梗阻/肠脂肪酸结合蛋白/肌酸磷酸激酶Key words
Intestinal Obstruction/intestinal fatty acid-binding protein/creatine kinase分类
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闫万里,胡凯强..肠脂肪酸结合蛋白和肌酸磷酸激酶在肠梗阻诊断中的意义[J].中国中西医结合外科杂志,2013,(6):624-626,3.