中国中西医结合外科杂志Issue(2)：163-166,4.DOI:10.3969/j.issn.1007-6948.2014.02.018
广痛消泡沫气雾剂对大鼠肛门水肿的作用
Intervention Effects of Guangtongxiao (广痛消)Foam Aerosol on Anus Edema Model in Rats
张媛 1赵宝明2
作者信息
- 1. 北京中医药大学 北京 100029
- 2. 北京中医药大学东直门医院肛肠科 北京 100700
- 折叠
摘要
Abstract
Objective To observe the pathological changes of edema in rat anus and the intervention ef-fects of Guangtongxiao (广痛消)foam aerosol. Methods SD rats were induced swelling of the anus by 0.16 mL croton mixture oil. The treatment group were given Guangtongxiao (广痛消)foam aerosols into the anus. All were killed after administration In the first three days respectively, taking perianal tissue staining pro-cess and microscopic pathologic changes observed in the blank group, model group, treatment group and the con-trol group. Results The rectal mucosa of the blank group was normal, of which the model group showed in acute inflammation. With increasing of drug delivery days, the ulcer of mucosa in the treatment group gradually improved, hyperemia and edema of the submucosa showed better, with less expansion of vascular congestion. The inflammatory changes of the control group were not obvious. Conclusion Croton oil injection can cause edema and inflammatory changes in SD rat anus; Guangtongxiao(广痛消)foam aerosol can lead to anti-inflam-matory and antioncotic to anal swelling of rats .关键词
广痛消泡沫气雾剂/巴豆油/大鼠水肿/病理改变Key words
Guangtongxiao(广痛消)foam aerosol/croton oil/anal edema in rats/pathological changes分类
生物科学引用本文复制引用
张媛,赵宝明..广痛消泡沫气雾剂对大鼠肛门水肿的作用[J].中国中西医结合外科杂志,2014,(2):163-166,4.
