中国中医药信息杂志Issue(11)：8-10,3.DOI:10.3969/j.issn.1005-5304.2013.11.004
臌胀片在HBeAg阳性慢性乙型病毒性肝炎治疗中的减毒增效作用
Attenuated and Synergistic Effect of Meteorism Tablets in Treatment of HBeAg-positive Chronic Hepatitis B
摘要
Abstract
Objective To observe the attenuated and synergistic effect of meteorism tablets in treating HBeAg-positive chronic hepatitis B patients. Methods Eighty patients of HBeAg-positive chronic hepatitis B were randomly divided into treatment group (meteorism tablets combined with telbivudine) and control group (telbivudine), and treated for one year. The changes of alanine aminotransferase (ALT) and aspartate aminotransferase (AST), the negative rate of HBV-DNA, the negative rate of HBeAg, HBeAg/HbeAb serological conversion rate, creatine kinase (CK) before and after treatment, and safety were observed. Results After treatment, biochemical response, virological response and HBeAg serological response was more significant in the treatment group than that in the control group (P<0.05). The percetage of patients with elevated CK in the treatment group was significantly lower than that in the control group (32.5% vs 60%, P<0.05). Conclusion Meteorism tablets combined with telbivudine has attenuated and synergistic effect in treating HBeAg-positive chronic hepatitis B patients.关键词
慢性乙型病毒性肝炎/乙肝e抗原/臌胀片/替比夫定/减毒增效Key words
chronic hepatitis B/HBeAg/meteorism tablets/telbivudine/attenuated and synergistic effect分类
医药卫生引用本文复制引用
王会丽,高天曙,杨小平,赵玉瑶..臌胀片在HBeAg阳性慢性乙型病毒性肝炎治疗中的减毒增效作用[J].中国中医药信息杂志,2013,(11):8-10,3.基金项目
河南省中医药继承与创新专项(072103810804) （072103810804）
