中国中医药信息杂志Issue(1)：69-70,71,3.DOI:10.3969/j.issn.1005-5304.2014.01.021
HPLC测定肝泰舒胶囊中獐牙菜苦苷含量
HPLC Determination of Swertiamarin in Gantaishu Capsules
摘要
Abstract
Objective To establish an HPLC method for determining the content of swertiamarin in Gantaishu capsules. Methods Using a Waters Symmetry C18 column (4.6 mm×250 mm, 5μm), the mobile phase was acetonitrile-0.02%phosphoric acid, with flow rate of 1.0 mL/min. The detection wavelength was at 250 nm, the column temperature was room temperature. Results The content of swertiamarin showed a good linear relationship in the range of 0.373 556-2.988 448 μg, r 2=1.000 0. The average recovery was 106.81%, and RSD was 3.7%. Conclusion This method is fast, accurate and simple with good reproducibility, which can be applied to the quality control of Gantaishu capsules.关键词
肝泰舒胶囊/含量测定/獐牙菜苦苷Key words
Gantaishu capsules/content determination/swertiamarin分类
医药卫生引用本文复制引用
郭珊珊,曹文静,笔雪艳,张清波..HPLC测定肝泰舒胶囊中獐牙菜苦苷含量[J].中国中医药信息杂志,2014,(1):69-70,71,3.基金项目
2011年度国家药品标准提高研究(586) （586）
