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超滤和醇沉纯化当归补血口服液对比研究

余琰 魏舒畅 马立新 范凌云

中国中医药信息杂志Issue(5):81-82,83,3.
中国中医药信息杂志Issue(5):81-82,83,3.DOI:10.3969/j.issn.1005-5304.2014.05.025

超滤和醇沉纯化当归补血口服液对比研究

Comparative Study on Ethanol Precipitation and Ultrafiltration of Danggui Buxue Oral Liquid

余琰 1魏舒畅 1马立新 2范凌云1

作者信息

  • 1. 甘肃中医学院,甘肃 兰州 730000
  • 2. 兰州佛慈制药股份有限公司,甘肃 兰州 730046
  • 折叠

摘要

Abstract

Objective To optimize the purification process of Danggui Buxue oral liquid by comparative study. Methods HPLC method and phenol-sulfuric acid method were used to determine astragaloside and total polysaccharides. The feasibility of alcohol precipitation and ultrafiltration were evaluated with clarify of purified samples and the retention rate of astragaloside and total polysaccharides as indexes. Results Ultrafiltration is superior to alcohol precipitation on retention rate of astragaloside and total polysaccharides, and clarity in purification process for Danggui Buxue oral liquid Conclusion The retention rate of effective components and clarity was higher, and the quality of samples was better by ultrafiltration.

关键词

醇沉/超滤/当归补血口服液/黄芪甲苷

Key words

ethanol precipitation/ultrafiltration/Danggui Buxue oral liquid/astragaloside

分类

医药卫生

引用本文复制引用

余琰,魏舒畅,马立新,范凌云..超滤和醇沉纯化当归补血口服液对比研究[J].中国中医药信息杂志,2014,(5):81-82,83,3.

基金项目

国家自然科学基金(81060345);甘肃省教育厅科研项目(1006B-02);甘肃中医学院中青年科研基金(09ZQ-3) (81060345)

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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