中国中医药信息杂志Issue(5)：95-97,3.DOI:10.3969/j.issn.1005-5304.2014.05.029
连翘败毒丸质量标准研究
Study on Quality Standard for Lianqiaobaidu Pills
武琳 1杨光 1黄菲1
作者信息
- 1. 北京同仁堂科技发展股份有限公司制药厂，北京 100079
- 折叠
摘要
Abstract
Objective To imporve the quality standard of Lianqiaobaidu Pills. Methods The TLC method was established for ephedrae herba, sophorae flavescentis radix, paeoniae radix rubra, and RP-HPLC methed was established for the determination of chlorogenic acid in Lianqiaobaidu Pills. Zorbax SB-C18 (4.6 mm×150 mm, 5 μm) column was used with methanol-acetonitrile (2∶1) - 0.04% phosphoric acid (10∶90) as the mobile phase at flow rate of 0.8 mL/min. The detection wavelength was 326 nm. Results TLC chromatographic spots were clear, and negative control had no interference. The linear range of chlorogenic acid was 0.042 2-0.464 2 µg (r=1), the average recovery (n=6) was 98.96%. Conclusion The method is simple, reliable, with strong exclusive feature, and suitable for quality control of Lianqiaobaidu Pills.关键词
连翘败毒丸/薄层色谱法/高效液相色谱法/绿原酸Key words
Lianqiaobaidu Pills/TLC/HPLC/chlorogenic acid分类
医药卫生引用本文复制引用
武琳,杨光,黄菲..连翘败毒丸质量标准研究[J].中国中医药信息杂志,2014,(5):95-97,3.
