中华耳科学杂志Issue(4)：588-592,5.DOI:10.3969/j.issn.1672-2922.2013.04.031
声强对下丘神经元时间分辨率的影响
The Effects of Sound Intensity on Temporal Resolution in Inferior Colliculus Neurons
摘要
Abstract
Objective To study effects of sound intensity on temporal resolution in phasic neurons in the inferior collicu-lus (IC). Methods Single unit recording was conducted in 40 adult guinea pigs. Gap stimuli was created by two Gaussian noise bursts that were separated by different gap durations:0, 1, 2, 3, 6, 9, 12, 24, 48 and 96 ms. The minimal gap threshold (MGT) as well as NB2 recovery and first spike latency (FSL) were analyzed under the following sound intensity exposures:minimum threshold (MT)+15 dB, MT+35 dB and MT+55 dB. Results Totally 166 neurons were recorded and data from 90 phasic neu-rons were presented. MGT was 8.81±1.08 ms, 7.08±0.78 ms and 7.11±0.67 ms, and FSL was 7.28±0.15 ms, 5.75±0.14 ms and 5.05 ± 0.13 ms for the three sound intensities respectively. There was no significant difference in MGT, FSL or NB2 recovery among the three groups. Conclusion Sound intensity appears to have no significant effect on temporal resolution of IC phasic neurons in guinea pigs, although the neuron response time shortens as sound intensity increases.关键词
声强/下丘/时间分辨率/豚鼠Key words
Sound intensity/inferior colliculus/temporal resolution/guinea pig分类
医药卫生引用本文复制引用
和守睆,Awad M. Almuklass,王坚,金晓杰..声强对下丘神经元时间分辨率的影响[J].中华耳科学杂志,2013,(4):588-592,5.基金项目
加拿大国家自然科学与工程研究所基金(NSERC):RG-PIN/250088-2007。 （NSERC）
