中华耳科学杂志Issue(1)：93-98,6.DOI:10.3969/j.issn.1672-2922.2014.01.023
国内高压氧联合药物治疗突发性耳聋临床疗效的Meta分析
Meta-analysis of the clinical efficacy of treatment of sudden deafness using hyperbaric oxygen combined with drug in China
库薇 1刘业海 1吴静 1王强 1童步生 1段茂利1
作者信息
- 1. 安徽医科大学第一附属医院耳鼻咽喉头颈外科 合肥230032
- 折叠
摘要
Abstract
Objective To evaluate the clinical efficacy of treatment of sudden deafness using hyperbaric oxygen com-bined with drug in recent years. Methods We searched nearly five years Chinese academic journals, Chinese digital library, VIP Information Resource System, Superstar Digital Library, Chinese Biomedical Literature Database, Wanfang database about hyperbaric oxygen therapy combined drug therapy of sudden deafness randomized controlled studies met the inclusion criteria for the evaluation of methodological literature from 2008 to 2012 , and RevMan5.1 software and the quality standards Meta-analysis of randomized controlled studies were included. Result 20 randomized controlled studies were analyzed, a to-tal of 2554 cases, of which 1,347 cases received hyperbaric oxygen therapy combined with drug treatment as treatment group, in contrast 1,207 cases received drug therapy alone was the control group. We found that the treatment group had a signifi-cant clinical effect than contrast group (P<0. 00001), and in addition ,the early use of hyperbaric oxygen therapy had better effect than the patients with hyperbaric oxygen of treatment at late stage (P<0. 00001). Conclusion The application of hyper-baric oxygen therapy combined with drug show better than drug therapy alone was, and the introduction of hyperbaric oxygen therapy,at earlier stage shows better results.关键词
高压氧/突发性耳聋/临床疗效Key words
Hyperbaric oxygenation/sudden hearing loss/Clinical effect分类
医药卫生引用本文复制引用
库薇,刘业海,吴静,王强,童步生,段茂利..国内高压氧联合药物治疗突发性耳聋临床疗效的Meta分析[J].中华耳科学杂志,2014,(1):93-98,6.
