中华耳科学杂志Issue(1)：109-111,3.DOI:10.3969/j.issn.1672-2922.2014.01.027
某航校飞行学员高频听力损失研究
Investigation of the High Frequency Hearing in an Aviation College
摘要
Abstract
Objective To track high frequency hearing changes among pilot cadets in an aviation school over consecu-tive two years and investigate the relationship between mitochondrial DNA (mtDNA) 4977 bp deletion and noise induced hear-ing loss. Methods One hundred and forty pilot students from Class 2008 in an aviation college were random included. Their hearing was followed for contiguous two years, with focus on high frequencies (4000, 6000 and 8000 Hz) and cumulative chang-es in high frequency hearing. Those with abnormal audiology results were tested for mtDNA4977 deletion. The SPSS 19.0 sta-tistics software was used for statistical analysis, with t-test being used to compare differences and chi square test to detect fre-quency of gene deletion in normal and abnormal hearing groups. Results There was change only at 4000 Hz in right ear (p<0.05) in senior pilot cadets over the two years. The rate of mtDNA4977 deletion differed among the normal and abnormal hear-ing groups (p<0.05). Conclusions Senior years pilot cadets are prone to have noise hearing loss and mtDNA4977 deletion may be a risk factor for noise induced hearing loss.关键词
飞行学员/高频听力/DNA/线粒体/基因/噪声/职业性Key words
Pilot cadets/High frequency hearing/DNA/Mitochondrion/Gene/Noise/Occupational分类
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李佳,董晶,郭睿,张红蕾,李大鹏,蔡庆,龚维熙,李丽,李平,李娟,郑伟..某航校飞行学员高频听力损失研究[J].中华耳科学杂志,2014,(1):109-111,3.基金项目
总后十二五重大课题项目 （）
