中华骨质疏松和骨矿盐疾病杂志Issue(1)：20-24,5.DOI:10.3969/j.issn.1674-2591.2014.01.004
成都地区291名绝经后女性骨密度与维生素D水平
Bone mineral density and serum-25-hydroxyvitamin D level of 291 postmenopausal women in Chengdu
万勇 1金小岚 1郎红梅 1艾智华 1游志清 1郭蔚 1程莹 1付静 1廖霞 1张学翠1
作者信息
- 1. 610083 成都，成都军区总医院内分泌科
- 折叠
摘要
Abstract
Objective To determine the level of serum vitamin D in postmenopausal women in Chengdu , and to explore the corelation with bone mineral density , age, menopausal age and body mass index (BMI).Methods Using cluster random sampling method , 291 postmenopausal women were recruited and their mean age is 63.9 ±9.7 years. Height, weight, age, menopausal age and general information were recorded at the same time .Their BMD at lumbar 2-4 (L2-L4), left femoral neck, total hip were measured by dual-energy X-ray absorptiometry (DXA).Simultaneously, the serum level of 25(OH)D3 was measured by enzyme-linked immunosorbent assay.To analyze the distribution of bone mass and serum 25(OH)D3 in postmenopausal women, they were divided into five groups according to age .Results More than half (52.2%) postmenopausal women suffered from osteoporosis .Morbidity rate of osteoporosis increased gradually with the age increasing , morbidity rate of elderly women over the age of 80 is the highest , which is 76.47%.The mean values of serum 25(OH)D3 was 18.37 ng/mL in 291 postmenopausal women.The prevalence of vitamin D deficiency is 68.38%in postmenopausal women .No linear correlation relationships was found between serum 25( OH) D3 and femoral neck BMD, total hip BMD, L2-L4 lumbar spine BMD.Serum 25(OH)D3 level was negatively correlated with BMI (P=0.000 ) .Conclusion Osteoporosis and vitamin D deficiency is very prevalent in postmenopausal women living in Cheng -du.To prevent osteoporotic frature , vitamin D supplementation should be recommended in postmenopausal women .关键词
绝经后骨质疏松/25羟维生素D/维生素D缺乏Key words
postmenopausal osteoporosis/25 hydroxyvitamin D/vitamin D deficiency分类
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万勇,金小岚,郎红梅,艾智华,游志清,郭蔚,程莹,付静,廖霞,张学翠..成都地区291名绝经后女性骨密度与维生素D水平[J].中华骨质疏松和骨矿盐疾病杂志,2014,(1):20-24,5.
