转化医学杂志Issue(2)：108-111,4.DOI:10.3969/j.issn.2095-3097.2014.02.012
基于嵌合抗原受体的肿瘤免疫治疗
Chimeric antigen receptor for immunotherapy of cancer
摘要
Abstract
Down-regulating the necessary component of immune system and suppressing pro-duction of immunosuppressive factors results in the tumor immune escape.Recently,the genetic modification of T cells with chimeric antigen receptors (CARs)was designed to solve the mechanism of escape immunosurveillance.The unique structure of CARs endows T cell tumor specific cytotoxici-ty and tumor antigen recognition ability.This adoptive antitumor immunotherapy develops rapidly and brings hope to the patients with tumors.关键词
嵌合抗原受体/过继免疫治疗Key words
Chimeric antigen receptors (CARs)/Adoptive immunotherapy分类
医药卫生引用本文复制引用
伍玉婷,梁华晟..基于嵌合抗原受体的肿瘤免疫治疗[J].转化医学杂志,2014,(2):108-111,4.基金项目
第十四批（2011年度）广西“新世纪十百千人才工程”第二层次人选专项资金资助 （）
