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电针不同介入时间对大鼠脑出血后行为学和脑组织形态学的影响

褚鑫 蔡恩丽 唐柱生 寇云芳 武煜明

针灸临床杂志Issue(2):68-70,3.
针灸临床杂志Issue(2):68-70,3.

电针不同介入时间对大鼠脑出血后行为学和脑组织形态学的影响

Intervention of Behavior and Brain Histomorphology after Experimental Intracerebral Hemorrhage(ICH) in Rats Treated by Electro-acupuncture(EA) at Different Time Points

褚鑫 1蔡恩丽 1唐柱生 1寇云芳 2武煜明1

作者信息

  • 1. 云南中医学院,云南昆明650500
  • 2. 贵阳中医学院,贵州贵阳550002
  • 折叠

摘要

Abstract

Objective:To study the intervention after experimental intracerebral hemorrhage ( ICH) in rats trea-ted by the electro-acupuncture ( EA) at different time points .Methods:192 rats were divided into normal con-trol group,sham operated group,ICH model group and EA group .Every group was divided into 6 h,24 h,72 h and 7 d subgroups .Produce the ICH models , evaluate the behavioral changes and observe the change of each rat's brain tissue appearance after the intervention .Results:Evaluate the behavioral changes before killing all the rats,there was no statistical significance between the subgroups ( P>0.05 );it was discovered that the model rat's brain tissue surrounding the hematoma was necrosis , containing lots of hemosiderin particles , phlegmasia cells infiltrated with the method of observation under light microscope .Compared with the model group ,the EA rats'damage was abatement , especially in the 6 h subgroup .Conclusion:The EA treatment at different time points ,especially the 6 h subgroups ,can lessen the dropsy of the brain tissue ,lighten the inflammatory reaction , protect the nerve cells and promote the function recovery of the brain tissue .

关键词

电针/脑出血/脑组织形态学/行为学

Key words

Electro-acupuncture/Intracerebral hemorrhage/Brain histomorphology/Behavior

分类

医药卫生

引用本文复制引用

褚鑫,蔡恩丽,唐柱生,寇云芳,武煜明..电针不同介入时间对大鼠脑出血后行为学和脑组织形态学的影响[J].针灸临床杂志,2014,(2):68-70,3.

基金项目

云南省应用基础研究面上项目,编号2011FZ157。 ()

针灸临床杂志

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