浙江医学Issue(19)：1748-1751,4.
不同浓度罗哌卡因联合芬太尼行硬膜外分娩镇痛的量效观察
Fentanyl combined with varying concentrations of ropivacaine in labor epidural analgesia
摘要
Abstract
Objective To investigate the optimal concentration of ropivacaine combined with fentanyl in labor epidural analgesia. Methods One hundred and twenty nul iparous women undergoing labor for delivery with epidural analgesia were randomized into four groups. Group F1 received 0.15%ropivacaine plus fentanyl 1μg/ml, group F2 0.12% ropivacaine plus fen-tanyl 1μg/ml, group F3 0.10%ropivacaine plus fentanyl 1μg/ml, group F4 0.08%ropivacaine plus fentanyl 1μg/ml. The block levels of epidural analgesia, the Bromage scores, Ramsey scores, fetal heart rate and uterine contraction in the course of labor were monitored;in addition, onset time of anesthesia, labor time, the cases with increased oxytocin use, visual analogue scale(VAS), Apgar scores of neonates and side- effect were also recorded. Results There were more cases with motor nerve block in groups F1 and F2 than those in groups F3 and F4 (P<0.05). There were more cases with increased oxytocin use in group F1 than other three groups (P<0.05). The onset of anesthesia was in group F4 was significantly longer than that in another three groups (P<0.05). The VAS scores at 30, 60 and 90min after injection in groupF4 was significantly higher than those in other three groups (P<0.05), and when drug withdraw the VAS in group F4 was significantly higher than groupF1 (P<0.05). Conclusion 0.10%ropivacaine combined with fentanyl 1μg/ml is the optimal dose with less motor block and high safety for epidural analgesia in la-bor.关键词
罗哌卡因/芬太尼/分娩镇痛Key words
Ropivacaine/Fentanyl/Labor analgesia引用本文复制引用
金豪杰,陈兰凤,高宝斌..不同浓度罗哌卡因联合芬太尼行硬膜外分娩镇痛的量效观察[J].浙江医学,2013,(19):1748-1751,4.
