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颈侧淋巴结阴性甲状腺乳头状微小癌中央区淋巴结转移的相关因素分析

叶昀亮 项颖颖 陈恩东 瞿金妙

浙江医学Issue(21):1872-1874,1885,4.
浙江医学Issue(21):1872-1874,1885,4.

颈侧淋巴结阴性甲状腺乳头状微小癌中央区淋巴结转移的相关因素分析

Risk factors of central lymph node metastasis in patients with cN0 papillary thyroid microcarcinoma

叶昀亮 1项颖颖 1陈恩东 1瞿金妙1

作者信息

  • 1. 325000 温州医科大学附属第一医院肿瘤外科
  • 折叠

摘要

Abstract

Objective To investigate the risk factors associated with central lymph node metastasis in patients with clinical lateral cervical lymph node negative (cN0) papil ary thyroid microcarcinoma (PTMC). Methods The clinical data of 392 patients with cN0 PTMC who underwent thyroidectomy and prophylactic central lymph node dissection in our hospital were collected. Ac-cording to the presence or absence of lymph node metastasis confirmed by postoperative pathologic examination, patients were divided into two groups, the clinicopathological features were compared between two groups. Results Univariate analysis showed that male, age<45y, maximum tumor diameter>7mm, multifocal carcinoma with total tumor diameter(TTD)>10mm were related to the central lymph node metastasis (P<0.05 or P<0.01). Multivariate analysis showed that male, age<45y, maximum tumor diameter>7mm, multifocal carcinoma with TTD>10mm were independent risk factors for central lymph node metastasis (P<0.05 or P<0.01). Conclusion Male PTMC patients aged<45y, maximum tumor diameter>7mm, multifocal carcinoma with TTD>10mm are more susceptible to the central lymph node metastasis and prophylactic central lymphadenectomy is recom-mended for these patients.

关键词

甲状腺肿瘤/中央区淋巴结转移/甲状腺乳头状微小癌

Key words

Thyroid neoplasms/Central lymph node metastasis/Papil ary thyroid microcarcinoma

引用本文复制引用

叶昀亮,项颖颖,陈恩东,瞿金妙..颈侧淋巴结阴性甲状腺乳头状微小癌中央区淋巴结转移的相关因素分析[J].浙江医学,2013,(21):1872-1874,1885,4.

浙江医学

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1006-2785

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