浙江医学Issue(22)：2004-2006,3.
正常中老年人群颅脑表观弥散系数特点分析
Apparent diffusion coefficient measurement of brain tissue in normal middle-aged and aged adults
摘要
Abstract
Objective To investigate the variability and trends of apparent diffusion coefficient (ADC) of different brain segments in normal middle- aged and aged Han adults. Methods Thirty Han normal adult subjects aged 40~70 without positive cerebral symptoms were divided into 3 age groups (40~49, 50~59, 60~70). Plain scan and diffusion weighted imaging (DWI) were performed by 3.0T MR in al subjects. The images were transferred to ADW 4.3 workstations for post- processing. Regions of interest were placed covering grey and white matter of frontal lobe, putamen, thalamus and cerebel um. The relationship of ADC value with different ages and cerebral regions was analyzed. Results The cerebral tissues of different location had differ-ent values in the same age group. The highest ADC value was detected in gray matter of the frontal lobe, fol owed by putamen, white matter of frontal lobe and the thalamus, and the lowest one was in cerebel um. There was no significant difference in ADCs between two sides of the same cerebral parts of different regions.(P>0.05).Although there was no significant difference in ADCs between grey and white matter of frontal lobe, putamen, thalamus and cerebel um of different age groups, the ADC value of the same region tended to increase with age. The changes of ADC value in subjects aged 40~60 presented a much slower rate and an upshift tendency was observed in subjects aged>60. Conclusion The ADC value of the same region in middle- aged and elderly people tended to increase with the age, particularly in subjects aged>60 years.关键词
磁共振成像/表观弥散系数/扩散加权成像Key words
Magnetic resonance imaging/Apparent diffusion coefficient(ADC)/Diffusion weighted imaging(DWI)引用本文复制引用
杨运俊,郭献忠,高凌云,郭翔,付军,陈伟建..正常中老年人群颅脑表观弥散系数特点分析[J].浙江医学,2013,(22):2004-2006,3.基金项目
浙江省科技计划项目 （）
