浙江医学Issue(24):2182-2185,4.
常见先天性心脏病介入治疗心肌损伤的影响因素分析
Influencing factors of myocardial damage in congenital heart disease interventional treatment
王珍全 1金佳蕙 1夏天和 1任跃 1荣星 1仇慧仙 1张松跃 1吴蓉洲 1陈其1
作者信息
- 1. 325000 温州医科大学附属育英儿童医院心血管科
- 折叠
摘要
Abstract
Objective To explore the influence factors of myocardial damage in the process of transcatheter therapy of congenital heart disease. Methods Transcatheter intervention of 200 cases of congenital heart disease were performed, includ-ing 61 cases of Ventricular septal defect(Group VSD), 69 cases of Atrial septal defect(Group ASD), 55 cases of Patent ductus ar-teriosus(Group PDA) and 15 cases of Pulmonary stenosis(Group PS). There were 17 cases of congenital heart disease angiogra-phy(Group angiography). The level of cTnI was measured by CLIA method before and 6h, 24h after operation, and the risk fac-tors of myocardial damage were analysed with single factor analysis and Logistic regression. Results The level of cTnI in-creased after operation in 159 cases, while remained normal in another 58 cases. Single factor analysis indicated that the my-ocardial damage was correlated with age of patient, body weight, pulmonary artery pressure, operation time, the size of the oc-cluder, the occluder release time and dose of contrast medium (P<0.01 or 0.05). Logistic regression showed that body weight, operation time, the size of the occluder, the occluder release time and dose of contrast medium were independent risk factors of myocardial damage. Conclusion Body weight, operation time, the size of the occluder, the occluder release time and dose of contrast medium may be important influence factors of myocardial damage in the process of transcatheter therapy of congenital heart disease.关键词
介入治疗/先天性心脏病/微小心肌损伤/肌钙蛋白IKey words
Interventional treatment/Congenital heart disease/Minor myocardial damage/Cardiac troponin I引用本文复制引用
王珍全,金佳蕙,夏天和,任跃,荣星,仇慧仙,张松跃,吴蓉洲,陈其..常见先天性心脏病介入治疗心肌损伤的影响因素分析[J].浙江医学,2013,(24):2182-2185,4.