浙江医学Issue(1)：23-25,3.
脑梗死患者血清胰岛素样生长因子-1与颈动脉粥样硬化斑块的关系
Relationship between serum levels of insulin-like growth factor-1 and carotid atheromatous plaques in patients with cerebral infarc-tion
张伟萍 1张宝荣2
作者信息
- 1. 310009 杭州，浙江大学医学院附属第二医院神经内科
- 2. 诸暨市人民医院神经内科
- 折叠
摘要
Abstract
Objective To investigate the relationship between serum levels of insulin- like growth factor- 1(IGF- 1)and carotid atheromatous plaques in patients with cerebral infarction. Methods One hundred patients with cerebral infarction and 50 healthy subjects were enrol ed in the study. Serum IGF- 1 levels were measured by ELISA and carotid artery was examined by ultrasonography in both groups. Patients with unstable plaque, stable plaque and non- plaque were classified by ultrasonic find-ings. Results The rate of carotid atheromatous plaque and unstable plaque in cerebral infarction patients were 67.0% and 42.0%respectively, which were significantly higher than that in control group (26.0% and 8.0%, P<0.01). Serum IGF- 1 level in unstable plaque group was significantly lower than that in stable plaque group and non- plaque group (P<0.01); while serum IGF- 1 level in stable plaque group was significantly lower than that in non- plaque group(P<0.05). Conclusion The incidence of carotid atheromatous plaque in patients with cerebral infarction is markedly increased; which is associated with the decreased serum IGF- 1 levels in patients.关键词
脑梗死/胰岛素样生长因子-1/颈动脉粥样硬化斑块Key words
Cerebral infarction/Insulin- like growth factor- 1/Carotid atheromatous plaque引用本文复制引用
张伟萍,张宝荣..脑梗死患者血清胰岛素样生长因子-1与颈动脉粥样硬化斑块的关系[J].浙江医学,2014,(1):23-25,3.
