浙江医学Issue(4)：307-310,4.
医院获得性耐甲氧西林金黄色葡萄球菌感染回顾性分析
Nosocomial infection of methicillin-resistant Staphylococcus aureus：a retrospective anylysis
邢茜 1江荣林 2马伟斌 2雷澍 2王灵聪 2智屹惠 2吴艳春 2黄立权 2朱美飞2
作者信息
- 1. 310053 杭州，浙江中医药大学第一临床医学院
- 2. 浙江中医药大学附属第一医院ICU
- 折叠
摘要
Abstract
Objective To investigate the risk factors, antibiotic susceptibility rate and clinical sequelae of nosocomial in-fection of methicil in- resistant Staphylococcus aureus (MRSA). Methods One hundred and ten strains of MRSA were isolated from Feb 2011 to Jan 2013. Drug resistance and clinical curative effect was retrospectively analyzed. Results MRSA infection mainly distributed in ICU, neurology and VIP Wards, and the strains of MRSA were mainly isolated from the sputum, the secretion of operative and skin wound, accounting for 68.2%, 11.2% and 8.2%, respectively. MRSA isolates were resistant to penicil ins, cefhalosporins and carbapenems; and the resistance to flouroquinolones, macrolides and aminologycosides varied among strains. The isolates were al sensitivive to teicoplanin, tigecycline, vancomysin, linezolid, furadantin and quinupristin/dalfopristin. In ICU over 90%patients with MRSA infection were those over age of 80, undergoing invasive procedures and long- time using broad- spectrum antibiotics;while in other wards most patients with MRSA infection were those undergoing operation and having long stay in the hospital. Conclusion Nosocomial MRSA infection usual y occurs in patients with multiple underlying diseases, undergoing invasive operation and the long- term using broad- spectrum antibiotics. The clinical isolates of MRSA are multiple drug resistant and the clinical manifestation were complex.关键词
耐甲氧西林金黄色葡萄球菌/感染危险因素/耐药率Key words
Methicil in- resistant staphylococcus aureus/High risk factors/Antibiotic resistance rate引用本文复制引用
邢茜,江荣林,马伟斌,雷澍,王灵聪,智屹惠,吴艳春,黄立权,朱美飞..医院获得性耐甲氧西林金黄色葡萄球菌感染回顾性分析[J].浙江医学,2014,(4):307-310,4.
