浙江医学Issue(6)：475-478,4.
高血压病患者心踝指数与B型钠尿肽水平相关性研究
Relationship between cardio-ankle vascular index and B-type natriuretic peptide levels in hypertensive patients
摘要
Abstract
Objective To investigate the relationship between cardio- ankle vascular indexes (CAVIs) and plasma B- type natriuretic peptide (BNP) levels in hypertensive patients. Methods Plasma BNP level, biochemical index, and CAVI were measured in 84 hypertensive patients (68±7)years;and echocardiography was also performed to evaluate left ventricular hypertrophy and function. Results Plasma BNP levels were significantly correlated with CAVI, age and course of disease (r=0.281, 0.269 and - 0.241, P<0.05). Multiple linear regression analysis revealed that CAVI was an independent determinant of BNP (β=0.282, P<0.05). In addition, CAVI was correlated with age, body mass index, and use of βblockers(r=0.359,- 0.234 and - 0.266, P<0.01 or 0.05); and regression analysis revealed that age was an independent determinant of CAVI (β=0.380, P<0.01). Conclusion The present study reveals that increased CAVI is an independent risk factor of elevated plas-ma BNP in hypertensive patients.关键词
高血压/动脉硬化/心踝指数/B型钠尿肽Key words
Hypertension/Arterial stiffness/Cardio- ankle vascular index/Btype natriuretic peptide引用本文复制引用
徐靓,严静,李莉,龚仕金,蔡国龙,戴海文,虞意华,刘秉宇,余海燕..高血压病患者心踝指数与B型钠尿肽水平相关性研究[J].浙江医学,2014,(6):475-478,4.基金项目
浙江省科技厅重大项目 （）
