浙江医学Issue(7)：565-567,3.
急性支气管肺炎患儿血浆HNP 1-3水平及其临床意义
Serum human neutrophil peptides levels in children with bronchopneumonia
摘要
Abstract
Objective To investigate the serum human neutrophil peptides 1- 3 (HNP 1- 3) levels in children with bron-chopneumonia and its value for etiological diagnosis. Methods Plasma samples were col ected from 88 children with bron-chopneumonia admitted between January and December 2012. Plasma HNP 1- 3 levels were detected by enzyme linked im-munosorbent assay(ELISA) at acute and convalescent stages of the patients. Independent sample t test was used to compare SA levels or iron levels between groups and Pearson correlation analysis was used to analyze correlation. Results Eighty- eight children with bronchopneumonia,including 53 males (60.2%) and 35 females (39.8%) were included in the study. The mean HNP 1- 3 level at the acute stage was 257.0±150.6 ng/ml, which was significant higher than that at the convalescent stage (215.6± 104.5mg/ml, t=2.12, P=0.036). Furthermore, plasma HNP1- 3 levels were correlated with white blood cell (r=0.283, P<0.001), neutrophil(r=0.275, P=0.001) and HS- CRP(r=0.273, P=0.001). Conclusion Plasma HNP 1- 3 level is significant higher at the a-cute stage than that in convalescent stage in children with bronchopneumonia and can be helpful in diagnosis of bacterial infec-tion.关键词
支气管肺炎/人中性粒细胞多肽/儿童Key words
Bronchopneumoniahuman/Neutrophil peptides/Children引用本文复制引用
朱银燕,华春珍,吴光声,李珊..急性支气管肺炎患儿血浆HNP 1-3水平及其临床意义[J].浙江医学,2014,(7):565-567,3.基金项目
浙江省医药卫生科技计划项目 （）
