肿瘤药学Issue(1)：62-65,4.DOI:10.3969/j.issn.2095-1264.2014.013
艾迪注射液联合化疗治疗晚期食管癌的临床观察
Clinical Study of Aidi Injection Combined with Chemotherapy in Treatment of Advanced Esophageal Cancer
胡青 1柳书芬 1周承鹏 1朱静娟 1张华卫 1肖志华2
作者信息
- 1. 中建三局武汉中心医院 肿瘤内科，湖北 武汉，430070
- 2. 湖北省肿瘤医院 内科，湖北 武汉，430070
- 折叠
摘要
Abstract
Objective To observe the therapeutic efficacy of Aidi injection combined with cisplation and 5-fluorouracil (PF regimen) chemotherapy in treatment of advanced esophageal cancer. Methods 46 cases of advanced esophageal cancer~were di-vided randomly into two groups. 24 patients of observation group were treated with Aidi injection (50 mL, d1~d14) combined with cisplation (DDP 30 mg·m-2, d1~d3) and 5-fluorouracil (5-Fu 500 mg·m-2, d1~d5). A cycle last 28 days and they had continu-ous two cycles. 22 patients of control group only received PF Chemotherapy as observation group. The therapeutic efficacy of the two groups was evaluated after two cycles of treatment. Results The overall response rates of observation group and control group were respectively 41.6% and 40.9%, and there was no statistically significant difference (P>0.05). The symptoms control rate of observation group was higher than that of control group (P<0.05). The life quality of patients in observation group was superior to the patients in control group (P<0.05). II~IV degree myelosuppression rate of observation group was lower than that of control group (P<0.05). Conclusion Aidi injection has the function of alleviating the symptoms and poisonous side-effect of chemotherapy medicine and improving life quality of patients with advanced esophageal cancer.关键词
食管肿瘤/联合化疗/艾迪注射液Key words
Esophageal Cancer/Chemotherapy/Aidi Injection分类
医药卫生引用本文复制引用
胡青,柳书芬,周承鹏,朱静娟,张华卫,肖志华..艾迪注射液联合化疗治疗晚期食管癌的临床观察[J].肿瘤药学,2014,(1):62-65,4.
