肿瘤药学Issue(1)：76-80,5.DOI:10.3969/j.issn.2095-1264.2014.016
子宫原始神经外胚层瘤2例并文献复习
2 Cases of Primitive Neuroectodermal Tumors of the Uterine and Literature Review
刘超霞 1张克强 1桂玲 1冉晓敏 1周萍 1肖凌志1
作者信息
- 1. 湖南省肿瘤医院/中南大学湘雅医学院附属肿瘤医院，湖南 长沙，410013
- 折叠
摘要
Abstract
Objective To investigate the clinical and pathological characteristics, treatment, and prognosis of Peripheral Primitive Neuroectodermal Tumors of the uterus. Methods 2 cases of primary Primitive Neuroectodermal Tumor of uterus were included in Hunan Provincial Tumor Hospital. A retrospective analysis was carried out to analyze the clinical characteristics, clinicopathological features, treatment and prognosis of these patients. Results 2 patients aged 17 and 44 years old respectively. The final diagnosis was established by the pathological diagnosis. Homer-Wright daisy-group was a specific pathologic feature of pPNET. Positive expression of the CD99 was observed in all cases.One case who was FIGO stages IVB received cytoreduc-tive surgery and chemotherapy, But recurred after only 4 months. and died 20 months . another patient who received tumorec-tomy was survived in 5 months of follow-up. Conclusion Peripheral primitive neuroectodermal tumor (PNET) of Uterus was a very rare disease. CD99 and Homer-Wright daisy-group were both specific markers for PNET. The therapy included surgery, chemotherapy and radiotherapy. The prognosis of the primitive neuroectodermal tumors was related to their stage. The clinical experiences about the primitive neuroectodermal tumors were still needed.关键词
子宫恶性肿瘤/原始神经外胚层瘤/子宫肿块/病理检查Key words
Uterine neopasms/Peripheral primitive neuroectodermal tumors/Uterine masses/Pathology分类
医药卫生引用本文复制引用
刘超霞,张克强,桂玲,冉晓敏,周萍,肖凌志..子宫原始神经外胚层瘤2例并文献复习[J].肿瘤药学,2014,(1):76-80,5.
