中南民族大学学报（自然科学版）Issue(3)：54-59,6.
大麻药生品和三种炮制品的急性毒性比较
Comparative Study on the Acute Toxicity of the Raw Radix Dolichosae and 3 Processed Products
摘要
Abstract
To evaluate the acute toxicity effects of the different processed products from Radix Dolichosae on mice, the LD50 value of the raw Radix Dolichosae, the products processed by bran , ginger and wine was determined by the classic methods .The acute toxic symptoms ,the death rate and the weight changes of mice were observed .The results indicated that among the raw Radix Dolichosae and 3 processed products , the LD50 values of the ginger processed product was the highest , then the bran processed product , the raw product ranked third , the wine processed product was the lowest .They are 17.93, 16.77, 12.11 and 9.45 g· kg-1 respectively.Hypokinesia, diarrhea, cardioacceleration and hypersalivation were the main acute toxicity symptoms .So it was concluded that the toxicity of Radix Dolichosae was significantly influenced by the different processing methods .Its toxic components and mechanisms remained further elucidation in the following study .关键词
大麻药/炮制/急性毒性Key words
Radix Dolichosae/processing/acute toxicity分类
化学化工引用本文复制引用
陈旅翼,兰洲,林亲雄,邓旭坤,赵喻丹,何凤莲..大麻药生品和三种炮制品的急性毒性比较[J].中南民族大学学报（自然科学版）,2013,(3):54-59,6.基金项目
国家科技部“十二五”科技支撑计划资助项目 （）
