国际医药卫生导报2014,Vol.20Issue(10):1388-1390,3.DOI:10.3760/cma.j.issn.1007-1245.2014.10.022
米非司酮联合甲氨蝶呤治疗异位妊娠的临床疗效分析
Mifepristone combined with methotrexate in treatment of ectopic pregnancy
郑穗瑾 1陈建国 2张秀果 1王黎 1章小东 3刘亮3
作者信息
- 1. 523945东莞,广东医学院附属厚街医院妇产科
- 2. 510080广州,广东省人民医院妇产科
- 3. 523945东莞,广东医学院附属厚街医院检验科
- 折叠
摘要
Abstract
Objective To explore the clinical efficacy of mifepristone combined with methotrexate in the treatment of ectopic pregnancy.Methods The data of patients with ectopic pregnancy were analyzed retrospectively.60 cases treated with methotrexate were set as a control group,and 60 cases treated with mifepristone combined with methotrexate as a treatment group.The β-HCG values,the size of mass,the hospital stays,and therapeutic efficacies were compared between the two groups after the therapy.Results The β-HCG values of the treatment group and the control group were (768.5 ± 79.3) mIU/mL and (918.0 ± 82.3) mIU/mL,respectively.The mass of the treatment group and the control group were (1.4 ± 0.8) cm and (2.8 ± 1.3) cm,respectively.The hospital stays of the treatmnent group and the control group were (8.3 ± 5.9) d and (13.1 ± 7.8) d,respectively.The β-HCG value,the size of mass,and the hospital stays of the treatment group are greatly lower than those of the control group,with statistical differences (P < 0.05).The therapeutic efficiency of the treatment group and the control group were 93.3% and 75.0%,respectively.The therapeutic efficiency of the treatment group was significantly higher than that of the control group.Conclusions Mifepristone combined with methotrexate in the treatment of ectopic pregnancy can be popularized in clinic,which has higher therapeutic efficiency than methotrexate alone.关键词
异位妊娠/米非司酮/甲氨蝶呤/临床疗效Key words
Ectopic pregnancy/ Mifepristone/ Methotrexate/ Clinical efficacy引用本文复制引用
郑穗瑾,陈建国,张秀果,王黎,章小东,刘亮..米非司酮联合甲氨蝶呤治疗异位妊娠的临床疗效分析[J].国际医药卫生导报,2014,20(10):1388-1390,3.