江苏大学学报（医学版）2014，Vol.24Issue(3)：255-259,5.DOI:10.13312/j.issn.1671-7783.y130274
多不饱和脂肪酸预防心房颤动复发的荟萃分析
Effects of polyunsaturated fatty acids on the recurrence of atrial fibrillation: a meta-analysis
李晓丽 1张宝伟 1刘玲玲 1赵龙 1沈冬丽 1孔彪 1张国辉1
作者信息
- 1. 江苏大学附属人民医院心内科,江苏镇江212002
- 折叠
摘要
Abstract
Objective:To evaluate the efficacy of polyunsaturated fatty acids (PUFA) on the recurrence of atrial fibrillation.Methods:The databases of Medline,EMBASE,Elsevier and Cochrane library were searched for randomized controlled trials.Quality assessment and data extraction were performed by two independent reviewers.Statistical analyses were conducted with RevMan 5.0 and Stata 10.0 software.Results:Studies with 1 839 patients were enrolled into this meta-analysis.Meta-analysis result showed that treatment with PUFA did not reduce the rate of recurrence of atrial fibrillation (RR =0.96,95 ％ CI 0.75-1.22,P =0.74).Sub-group analysis showed that PUFA could reduce the rate of recurrence of atrial fibrillation in the sub-group that patients were treated with PUFA more than 28 days before the following-up (RR =0.720,95 ％ CI 0.622-0.835,P ＜ 0.01).Conclusion:The results of the present meta-analysis of randomized controlled trials suggested that treatment with PUFA did not reduce the rate of recurrence of atrial fibrillation.关键词
多不饱和脂肪酸/房颤/荟萃分析Key words
polyunsaturated fatty acids/ atrial fibrillation/ meta-analysis分类
医药卫生引用本文复制引用
李晓丽,张宝伟,刘玲玲,赵龙,沈冬丽,孔彪,张国辉..多不饱和脂肪酸预防心房颤动复发的荟萃分析[J].江苏大学学报（医学版）,2014,24(3):255-259,5.
