国际医药卫生导报2014，Vol.20Issue(14)：2030-2033,4.DOI:10.3760/cma.j.issn.1007-1245.2014.14.004
D-CIK治疗降低外周血EMT相关分子表达的初步研究
D-CIK therapy to reduce the expression of Twist and Vimentin mRNA in circulating colorectal cancer cells
摘要
Abstract
Objective To investigate the significance of change of EMT-associated proteins in colon cancer patients treated with D-CIK.Methods The study included 34 cases of advanced colon cancer undergoing D-CIK treatment.The EMT-associated molecules in peripheral blood were detected before and after treatment.Treatment-related adverse reactions were also observed during treatment progress.Result D-CIK treatment reduced the expression of Twist and Vimentin in peripheral blood of colon cancer patients,and no significant adverse reactions were observed.Conclusion D-CIK treatment can reduce the expression of Twist and Vimentin mRNA in circulating colorectal cancer cells.关键词
D-CIK/结肠癌/循环肿瘤细胞/表皮间质转化Key words
D-CIK/ Colon cancer/ Circulating tumor cell/ Epithelial-mesenchymal transition引用本文复制引用
马磊,金川,邓旭斌,陆勤,刘晓燕,陈文晟,邹青峰..D-CIK治疗降低外周血EMT相关分子表达的初步研究[J].国际医药卫生导报,2014,20(14):2030-2033,4.基金项目
广东省科技厅科研项目(2011B080701021) （2011B080701021）
广州医学院科研项目(2013C61) （2013C61）
