国际医药卫生导报2014，Vol.20Issue(15)：2222-2225,4.DOI:10.3760/cma.j.issn.1007-1245.2014.15.003
影响肺结核密切接触者发病的因素分析
A case-control study on risk factors of tuberculosis close contacts
摘要
Abstract
Objective To investigate the risk factors of tuberculosis close contact and provide scientific clues for tuberculosis prevention.Methods 289 tuberculosis patients as cases and 595 disease-free as controls,were selected according to registered data and follow-up system of smear-positive pulmonary tuberculosis patients and their close contacts in our hospital from 2011 to 2013.Results Univariate analysis demonstrated that factors such as history of Bacillus Calmette Guerin (BCG) vaccination,housing ventilation,interior hygiene,meat and eggs consumption,smoke,history of chronic bronchitis or diabetes,working hours per day,and the work environment conditions had significant association with pulmonary tuberculosis.Furthermore,multivariate logistic analysis showed that smoke,history of chronic bronchitis or diabetes and working hours ≥ 12 per day offered an adverse role on tuberculosis risk,while history of BCG vaccination,favorable housing ventilation or work environment,and meat and eggs consumption (＞4 times/week) contributed an protective effect on tuberculosis.Conclusion Tuberculosis incidence of close contacts were closely related to their personal health quality,and their living and working environment.Individual giving-up smoking education should be strengthened,and improving environmental ventilation and health in housing and public places could be effective for pulmonary tuberculosis prevention and control.关键词
肺结核/密切接触者/影响因素Key words
Pulmonary tuberculosis/ Close contacts of tuberculosis/ Risk factors引用本文复制引用
杜正新,罗少霞,何凯立,谭青云..影响肺结核密切接触者发病的因素分析[J].国际医药卫生导报,2014,20(15):2222-2225,4.基金项目
广东省科技厅项目(粤科函社字[2010] 1096号) （粤科函社字[2010] 1096号）
广州市医药卫生科技一般引导项目(201102A213169) （201102A213169）
