国际医药卫生导报2014，Vol.20Issue(15)：2303-2305,3.DOI:10.3760/cma.j.issn.1007-1245.2014.15.031
宫腔镜病灶切除术联合药物治疗子宫瘢痕妊娠的临床分析
Clinical analysis on hysteroscopic resection of lesions combined with medications for cesarean scar pregnancy
陈海英 1邓桂珍1
作者信息
- 1. 514031 梅州市嘉应学院医学院附属医院妇产科
- 折叠
摘要
Abstract
Objective To explore the clinical efficacy of hysteroscopic resection of lesions combined with methotrexate (MTX) and mifepristone in the treatment of cesarean scar pregnancy (CSP).Methods 32 women with early CSP diagnosed by transvaginal color Doppler ultrasound who had been treated in our hospital during from October 2009 to October 2013 were retrospectively analyzed.The women were randomly divided into two groups according to different therapies.Group A (control group) received dilatation and curettage under type B-ultrasonic monitoring one week after treatment with intracapsular infusions of MTX combined with oral mifepristone; whereas group B (study group) received hysteroscopic resection of lesions plus dilatation and curettage and intralesional injections under ultrasonic monitoring one week following therapies with intracapsular infusions of MTX combined with oral mifepristone.The amount of vaginal bleeding and the decrease in blood B-HCG after treatment,time to onset of the menstrual cycle,and efficacy of therapies were compared between the two groups.Results One week after treatment,B-HCG level was markedly declined in both groups,which was more than 50％ of the baseline.The percentage of B-HCG decrease was significantly greater,and time to return of B-HCG to normal level and to return of a normal menstrual cycle was shorter in group B [(14.0 ± 5.1) days and (30.00 ± 4.40)days] than in those in group A.No complications occurred.Conclusions Hysteroscopic resection of lesions combined with methotrexate is more effective than medication alone in the treatment of cesarean scar pregnancy.关键词
宫腔镜/瘢痕妊娠/甲氨蝶呤(MTX)Key words
Hysteroscopy/ Cesarean scar pregnancy/ Methotrexate引用本文复制引用
陈海英,邓桂珍..宫腔镜病灶切除术联合药物治疗子宫瘢痕妊娠的临床分析[J].国际医药卫生导报,2014,20(15):2303-2305,3.
