国际医药卫生导报2014，Vol.20Issue(16)：2482-2484,3.DOI:10.3760/cma.j.issn.1007-1245.2014.16.025
62例极低/超低出生体重儿晚发型败血症的临床分析
Late-onset sepsis in very and extremely low birth weight infants
莫文辉 1杨杰 2李奕 1罗耀明1
作者信息
- 1. 528031 佛山禅城区中心医院
- 2. 510010广州,广东省妇幼保健院
- 折叠
摘要
Abstract
Objective To investigate the features of late-onset sepsis (LOS) in the very low birth weight(VLBW) infants and extremely low birth weight(ELBW) infants,and to explore the laboratory examination for the early detection of LOS in premature infants.Methods Data were collected from 62 VLBW/ELBW infants diagnosed with LOS and admitted into the neonatal intensive care units of our hospital and Gnangdong Women and Children' s Hospital from January,2010 to June,2013.60 VLBW/ELBW infants without sepsis admitted into these two hospitals' departments of neonate pediatrics in the same period were randomly selected as a control group.The risk factors,main infection and laboratory examination indexes were retrospectively analyzed in VLBW/ ELBW infants with LOS.Results The gestational age,mechanical ventilation,central venipuncturation,and the time of parenteral nutrition were the major risks leading to LOS in VLBW/ELBW infants.The main approaches of infection were respiratory tract infection,intestinal infection,and skin infection.The clinical symptoms of LOS were different.The first symptoms were mainly abdominal distension or stomach retention,apnea or blood oxygen fluctuations,anhelation,poor response,fever,and tachycardia.And the analysis showed that CRP and PCT significantly increased in the early stage of LOS,but the WBC and platelet didn' t significantly change.Blood culture indicated that the main bacteria was Gram negative bacteria.Conclusions VLBW/ELBW infants were susceptibility to the LOS.Clinical features don' t show in the early stage of LOS.Infection can be found out detecting CRP and PCT.关键词
极低出生体重儿/超低出生体重儿/晚发/败血症Key words
Very low birth weight infant/ Extremely low birth weight infant/ Late-onset/ Sepsis引用本文复制引用
莫文辉,杨杰,李奕,罗耀明..62例极低/超低出生体重儿晚发型败血症的临床分析[J].国际医药卫生导报,2014,20(16):2482-2484,3.
