国际神经病学神经外科学杂志2014，Vol.41Issue(5)：430-432,3.
丁苯酞软胶囊治疗椎动脉优势型眩晕疗效观察
Clinical efficacy of dl-3-butylphthalide soft capsules in treatment of vertigo caused by vertebral artery dominance: a randomized controlled trial
阳娜 1谭利明 2杨利 2周仕钧 1唐海洋1
作者信息
- 1. 湘潭市第一人民医院神经内科,湖南省湘潭市411100
- 2. 中南大学湘雅二医院神经内科,湖南省长沙市410011
- 折叠
摘要
Abstract
Objective To evaluate the clinical efficacy and safety of dl-3-butylphthalide (NBP) soft capsules in the treatment of posterior circulation ischemia vertigo (PCIV) due to the hemodynamic effect of one dominant vertebral artery.Methods Seventy-six patients with the first onset of vertigo were selected,among whom PCIV was detected by head magnetic resonance angiography.The PCIV patients were randomly assigned to treatment and control groups,which were given aspirin and atorvastatin calcium therapy and NBP soft capsules combined with aspirin and atorvastatin calcium therapy,respectively.The degree of symptom alleviation and the rate of abnormal transcranial Doppler (TCD) blood flow were measured after 14 days of treatment.Results The overall response rates were 92.1％ in the treatment group and 65.8％ in the control group,showing a significant difference between groups (P ＜ 0.05).The rate of abnormal TCD flow findings in basilar artery decreased in both groups after treatment,and the decrease was higher in the treatment group than in the control group (47.4％ vs 57.9％,P ＜ 0.05).Conclusions Use of NBP soft capsules is an effective and safe therapy for PCIV caused by vertebral artery dominance.关键词
丁苯酞/椎动脉优势/眩晕/后循环缺血Key words
dl-3-butylphthalide/ vertebral artery dominance/ vertigo/ posterior circulation ischemia引用本文复制引用
阳娜,谭利明,杨利,周仕钧,唐海洋..丁苯酞软胶囊治疗椎动脉优势型眩晕疗效观察[J].国际神经病学神经外科学杂志,2014,41(5):430-432,3.
