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胃肠道外间质瘤预后因素分析

高业博 花宝金 付强 谢建国

肿瘤防治研究2014,Vol.41Issue(12):1322-1325,4.
肿瘤防治研究2014,Vol.41Issue(12):1322-1325,4.DOI:10.3971/j.issn.1000-8578.2014.012.015

胃肠道外间质瘤预后因素分析

Prognostic Factors for Extragastrointestinal Stromal Tumors Patients

高业博 1花宝金 2付强 1谢建国3

作者信息

  • 1. 100053北京,中国中医科学院广安门医院肿瘤科
  • 2. 100029北京,北京中医药大学临床医学院
  • 3. 450008郑州,郑州大学附属医院河南省肿瘤医院普外科
  • 折叠

摘要

Abstract

Objective To explore clinical features and prognostic factors of extragastrointestinal stromal tumors(EGSTs).Methods We retrospectively analyzed clinicopathological data of 35 EGSTs patients admitted from January 2006 to May 2011 in Henan Tumor Hospital by SPSS17.0.Kaplan-Meier and Cox regression(forward stepwise regression) analysis were used to evaluate the prognostic factors(P<0.05).Results 1-,2-and 3-year survival rates of all EGST patients were 81.6%,57.3% and 35.3%; 18 patients (51.4%) with R0 resection developed recurrence or metastasis.Cox regression analysis showed that the surrounding tissue invasion (RR:3.386,95% CI:1.142-10.044),tumor recurrence or metastasis (RR:2.269,95% CI:1.055-4.880),tumor hemorrhage necrosis (RR:3.015,95%CI:1.120-4.880) and tumor rupture (RR:8.085,95%CI:2.517-25.967) were independent prognostic factors.Conclusion EGIST symptoms are dormant and difficult to diagnose,with large volume at first.Surrounding tissue invasion,tumor recurrence or metastasis,tumor hemorrhage necrosis and rupture are independent prognostic factors.

关键词

胃肠道外间质瘤/临床特征/预后因素

Key words

Extragastrointestinal stromal tumors(EGSTs)/ Clinical features/ Prognosis factors

分类

医药卫生

引用本文复制引用

高业博,花宝金,付强,谢建国..胃肠道外间质瘤预后因素分析[J].肿瘤防治研究,2014,41(12):1322-1325,4.

肿瘤防治研究

OA北大核心CSCDCSTPCD

1000-8578

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