中国中西医结合杂志2014，Vol.34Issue(12)：1453-1456,4.DOI:10.7661/CJIM.2014.12.1453
通腑净化汤对创伤后脓毒症休克患者血流动力学和组织氧代谢的影响
Effect of Tongfu Jinghua Decoction on Hemodynamics and Tissue Oxygen Metabolism in Patients with Post-traumatic Sepsis Shock
摘要
Abstract
Objective To explore the effect of Tongfu Jinghua Decoction (TJD) on hemodynamics and tissue oxygen metabolism in patients with post-traumatic sepsis shock.Methods Totally 60 patients were randomly assigned to the treatment group and the control group,30 in each group.Patients in the treatment group took TJD or were administered with TJD by nasal feeding in combined with conventional Western medical treatment,while patients in the control group only received conventional Western medical treatment.Changes of each index in hemodynamics and tissue oxygen metabolism were observed before treatment,and at 6,12,24,and 48 h after treatment.Results Compared with before treatment in the same group,hemodynamic changes were significantly improved at each time point in the two groups.All indices of tissue oxygen metabolism at each time point of the two groups were significantly improved,except changes of O2extraction ratio (ER) after treatment in the control group (P ＜0.05,P ＜0.01).Compared with the control group in the same period,heart rate (HR),systemic vascular resistance (SVR),and cardiac output (CO) were significantly improved with statistical difference (P ＜0.05,P ＜ 0.01).Mean arterial pressure (MAP),central venous pressure (CVP),and cardiac index (CI) were significantly improved at 6,12,and 24 h after treatment with statistical difference (P ＜0.05,P ＜0.01).Each index of tissue oxygen metabolism in the treatment group were all improved at each time point with statistical difference (P ＜0.05,P ＜0.01).Conclusion TJD combined with conventional Western medical treatment could quickly improve hemodynamics and tissue oxygen metabolism disorder in patients with septic shock,and its curative effect was superior to that of conventional Western medical treatment alone.关键词
通腑净化汤/脓毒症休克/血流动力学/组织氧代谢Key words
Tongfu Jinghua Decoction/ septic shock/ hemodynamics/ tissue oxygen metabolism引用本文复制引用
杨铁柱,李良业,韩卢丽,王凤英..通腑净化汤对创伤后脓毒症休克患者血流动力学和组织氧代谢的影响[J].中国中西医结合杂志,2014,34(12):1453-1456,4.基金项目
河南省科技厅成果(No.豫科鉴字[2013]第345号) （No.豫科鉴字[2013]第345号）
