国际医药卫生导报2015，Vol.21Issue(1)：56-57,60,3.DOI:10.3760/cma.j.issn.1007-1245.2015.01.017
药学干预对鲍曼不动杆菌耐药性与抗菌药物使用强度的成效对比
Effect pharmaceutical intervention on drug resistance of acinetobacter baumannii and antibiotics use intensity
摘要
Abstract
Objective To explore Discussion on effect pharmaceutical intervention on the drug resistance of acinetobacter baumannii and the antibiotics use intensity.Methods The results of drug sensitivity of 263 strains of acinetobacter baumannii in the patient hospitalizedinto our hospital from January,2012 to January,2014 and the clinical data of their antibacterial drug usage were collected and analyzed with SPSS 18.0 statistical software.Results The drug resistant rates of acinetobacter baumannii against ceftriaxone and levofloxacin increased from 69.84％ and 37.69％ to 87.26％ and 59.81％ in one year,against imipenem from 8.69％ to 11.32％,and against cefoperazone / sulbactam in two years were 7.91％ and 4.05％ respectively with good sensitivity.The drug resistant rate of acinetobacter baumannii against ceftazidime positively correlated with cefoperazone / sulbactam; the correlation coefficiency was 0.923.The drug resistant rate of acinetobacter baumannii against amikacin negatively correlated with the dosage of piperacillin / tazobactam; the correlation coefficient was-0.913.Conclusions Drug resistance of acinetobacter baumannii increases with the use of antibiotics year by year and associates with the type and use intensity of antibiotics.At hospital,antibiotic use should be restricted and regularly changed to reduce the generation of super resistant bacteria.关键词
鲍曼不动杆菌/耐药性/抗菌药物Key words
Acinetobacter baumannii/ Drug resistance/ Antimicrobial agents引用本文复制引用
苏丽..药学干预对鲍曼不动杆菌耐药性与抗菌药物使用强度的成效对比[J].国际医药卫生导报,2015,21(1):56-57,60,3.
