摘要
Abstract
Objective To investigate the clinical value of major myocardial damage markers in differential diagnosis of viral myocarditis (VMC) and acute upper respiratory infection (AURI) in children.Methods 55 children with AURI and 47 children with VMC in our hospital from April 2013 to April 2014 were selected,with 50 healthy children as a control.Myocardial enzyme indicators,including lactic dehydrogenase (LDH),α-hydroxybutyrate dehydrogenase (α-HBDH),creatine kinase (CK) and CK-MB,myocardial protein indicators,including cardiac troponin Ⅰ (cTnⅠ) and myohemoglobin (Myo),were compared among three groups with one-way ANOVA and chi-square test.Results There were statistically significant differences in CK and CK-MB among three groups (F=5.08,4.86; P＜0.05),no statistically significant differences in LDH and α-HBDH (F=1.24,1.08; P＞0.05).There were statistically significant differences in CK and CK-MB between VMC group and control group (t=2.693,2.019; P＜0.05); there was statistically significant difference in CK between AURI group and control group (t=2.451,P＜0.05),without statistically significant difference in CK-MB (t=1.708,P＞0.05).There was statistically significant difference in positive rate of cTnⅠ,Myo and CK-MB between VMC group and AURI group (x 2=9.878,P＜0.01).Conclusion Combined tests of cTnⅠ,Myo and CK-MB/CK(％CK-MB) allow clinicians to determine similarities between viral myocarditis and acute upper respiratory infection more accurately and quickly,hence avoid missed diagnosis and misdiagnosis.关键词
儿童病毒性心肌炎/急性上呼吸道感染/心肌酶/心肌蛋白/诊断Key words
Children's viral myocarditis/ Acute upper respiratory infection/ Cardiac enzymes/ Myocardial protein/ Diagnosis
