摘要
Abstract
Objective: To investigate the clinical features of intrahepatic cholangiocarcinoma (ICC), for increasing the understanding of this disease, and reducing its misdiagnosis and inappropriate treatment.
<br> Methods: The clinical date of 42 ICC patients (ICC group) and 80 hepatocellular carcinoma (HCC) patients (HCC group) with pathological confirmation, admitted from January 2005 to December 2013, were retrospectively analyzed.
<br> Results: In ICC group compared with HCC group, there was no gender difference (number of male cases was more than female cases in HCC group); the number of cases with past or present cholelithiasis was increased, and most stones were on the same side of the tumors; the positive rate of HbsAg and AFP as well as their detection values were decreased, while the positive rate of CA19-9 and proportion of cases with high γ-GT level as well as their detection values were increased; the imaging proifles were more characterized by enlargement of abdominal lymph nodes, bile duct stones, peritumoral bile duct dilation and liver capsule retraction or lobe atrophy; the preoperative misdiagnosis rate was high, tumor cells showed histologically poor differentiation, and abdominal lymph node metastasis rate was increased; liver tumor resection plus abdominal lymphadenectomy was the most adopted procedure. All the difference had statistical signiifcance (allP<0.05).
<br> Conclusion: ICC has some clinical features different from those of HCC, and a better understanding of ICC may reduce its misdiagnosis and wrong treatment.关键词
胆管肿瘤/胆管,肝内/癌,肝细胞/诊断,鉴别Key words
Bile Duct Neoplasms/Bile Ducts, Intrahepatic/Carcinoma, Hepatocellular/Diagnosis, Differential分类
医药卫生
