江苏大学学报（医学版）2015，Vol.25Issue(2)：159-163,5.DOI:10.13312/j.issn.1671-7783.y140297
PCI术前强化应用他汀类药物预防心肌无复流的Meta分析
Prevention of intensive statins therapy before percutaneous coronary intervention in myocardial no-reflow phenomenon : a meta-analysis
钟健 1付强 2朱可 2张倩2
作者信息
- 1. 江苏大学医学院,江苏镇江212013
- 2. 徐州市中心医院心内科,江苏徐州221009
- 折叠
摘要
Abstract
Objective:To systematically evaluate the prevention of intensive statins therapy and standard statins therapy before percutaneous coronary intervention for acute coronary syndrome patients in no-reflow phenomenon of myocardium.Methods:PubMed,Medline,Science,Embase,Cochrane Library,CNKI,Wanfang and VIP were searched to collect randomized controlled trials (RCTs) of prevention of intensive statins therapy before percutaneous coronary intervention in no-reflow phenomenon of myocardium.Retrial time was from the inception of those database to July,2014.Jadad score were used for literature evaluation and information extraction.Meta-analysis was performed by RevMan 5.3 software.Results:Totally six RCTs that contained 855 acute coronary syndrome patients with percutaneous coronary intervention were enrolled,in which the group of intensive statins therapy had 429 cases and the group of standard statins therapy had 426 cases.Meta-analysis showed that the rate of no-reflow significantly decreased in the intensive statins therapy cases compared with that of the standard statin therapy cases undergoing percutaneous coronary intervention [9.56％ vs 26.06％,OR =0.28,95 ％ CI (0.19,0.41)].Conclusion:The intensive statins therapy before percutaneous coronary intervention can significantly reduce the incidence of no-refiow in acute coronary syndrome patients during operation compared with standard statins therapy.关键词
他汀类药物/急性冠脉综合征/经皮冠脉介入治疗/无复流/Meta分析Key words
statins/acute coronary syndrome/percutaneous coronary intervention/no-reflow/meta-analysisgs分类
医药卫生引用本文复制引用
钟健,付强,朱可,张倩..PCI术前强化应用他汀类药物预防心肌无复流的Meta分析[J].江苏大学学报（医学版）,2015,25(2):159-163,5.
