中国美容医学Issue(4)：32-35,4.
CD44v3和CD44v5在口腔黏液表皮样癌中的表达及临床意义
Expression and clinical significance of CD44v3 and CD44v5 in oral mucoepidermoid carcinoma
马笮 1胡姗姗 2周洋 1孙昊量 1李慧 1栗巧玲1
作者信息
- 1. 牡丹江医学院红旗医院一分院 口腔科 黑龙江 牡丹江 157011
- 2. 牡丹江医学院红旗医院一分院 眼科 黑龙江 牡丹江 157011
- 折叠
摘要
Abstract
Objective To detect the expression of the cell surface adhesion molecule CD44v3 and CD44v5 in oral mucoepidermoid carcinoma (OMC),and to explore the relationship between the two and the occurrence,pathological grade and clinical stage of OMC. Methods Immunohistochemical staining was used to detect the exprssion of CD44v3 and CD44v5 protein in 40 cases of OMC in paraffin embedded specimens, and were statistically analyzed. Results CD44v3 and CD44v5 expression rates in OMC compared with the control group was significantly higher ( <0.05), no significant differences between pathological grade, and clinical stage ( >0.05). Conclusion OMC in the lymph node metastasis,CD44v3 and CD44v5 may play an important role,CD44v3,CD44v5 may be one of the important indexesto understand the transfer of OMC lesion development and the biological behavior of lymph node.关键词
口腔黏液表皮样癌/CD44v3/CD44v5/免疫组化Key words
oralmucoepidermoid carcinoma/CD44v3/CD44v5/immunohistochemistry分类
医药卫生引用本文复制引用
马笮,胡姗姗,周洋,孙昊量,李慧,栗巧玲..CD44v3和CD44v5在口腔黏液表皮样癌中的表达及临床意义[J].中国美容医学,2015,(4):32-35,4.
