中国组织工程研究Issue(52)：8365-8370,6.DOI:10.3969/j.issn.2095-4344
硫酸钙人工骨椎弓根植骨修复胸腰段椎体爆裂性骨折
Calcium sulfate artificial bone for repair of thoracolumbar burst fractures
摘要
Abstract
BACKGROUND:Calcium sulfate artificial bone acts as a kind of bone graft material within the vertebral body, has good fusion effect and can effectively correct sagittal deformity and sequence to maintain the vertebral height. <br> OBJECTIVE:To assess the clinical effects of calcium sulfate artificial bone in the treatment of thoracolumbar burst fractures. <br> METHODS: Forty-six thoracolumbar burst fracture patients were randomly divided into a bone graft group (21 patients undergoing treatment with calcium sulfate artificial bone) and a non-bone graft group (25 patients undergoing vertebroplasty alone). The efficacy of the two types of surgery was compared in terms of postoperative recovery time, visual analog scale score at the final folow-up, anterior vertebral height, incidence of ghost vertebral phenomenon and failure rate of internal fixation. <br> RESULTS AND CONCLUSION:Al patients were folowed up for 12 months. Patients in the bone graft group and non-bone graft group were folowed up for an average of 18.7 months and 17.48 months, respectively. The postoperative recovery time of patients in the bone graft group was shorter than that in the non-bone graft group (P=0.002); the incidence of ghost vertebral phenomenon and internal fixation failure rate in the bone graft group were lower than those in the non-bone graft group (P=0.036, P=0.038). However, there were no significantly statistical differences between two groups in visual analog scale score at the final folow-up and anterior vertebral height at different time (alP > 0.05). These findings indicate that calcium sulfate artificial bone for thoracolumbar burst fractures is effective and safe, which is superior to vertebroplasty alone.关键词
生物材料/骨生物材料/硫酸钙人工骨/胸腰段椎体爆裂性骨折/椎体成形/手术疗效Key words
Subject headings:calcium sulfate/spinal fractures/vertebroplasty分类
医药卫生引用本文复制引用
龙浩,肖杰,邹伟,吴陈,张洋,冯明星,符勇..硫酸钙人工骨椎弓根植骨修复胸腰段椎体爆裂性骨折[J].中国组织工程研究,2014,(52):8365-8370,6.基金项目
贵阳市卫生局资助项目Funding:the grant from Guiyang Health Bureau Funding:the grant from Guiyang Health Bureau （）
