中国组织工程研究Issue(52)：8498-8503,6.DOI:10.3969/j.issn.2095-4344
壳聚糖支架应用在组织工程中：组成复合支架及改性支架的前景
Development of chitosan and its derivative scaffolds for tissue engineering
摘要
Abstract
BACKGROUND:Chitosan has an excelent performance, such as non-toxic, non-irritating, biocompatibility and biodegradability, which can promote adhesion and proliferation of a variety of tissue cels. Chitosan has become a research hotspot in the tissue engineering scaffold. <br> OBJECTIVE:To investigate the application development of chitosan and its derivative scaffolds in tissue engineering. <br> METHODS: A computer-based search of China Biology Medicine Database and PubMed was performed for articles related to chitosan and its derivative scaffolds published from 1989 to 2013. The keywords were “chitosan, scaffold, tissue engineering” in Chinese and English, respectively. <br> RESULTS AND CONCLUSION:There are several aspects about the major use of chitosan and its derivative scaffolds for tissue engineering. One is to act as a cel culture scaffold; the second is to act as a compound scaffold which is combined with other materials; and the third is to be used as a modified scaffold. Chitosan and its derivatives are a kind of natural polymer material which has unique biological activity. It has broad application prospects in tissue engineering research. To be combined with other biomaterials or to prepare modified scaffolds wil be the future research focus of chitosan and its derivatives.关键词
生物材料/骨生物材料/壳聚糖/衍生物/支架/组织工程/广东省自然科学基金Key words
Subject headings：chitosan/tissue engineering/stents分类
医药卫生引用本文复制引用
王腾彬,朱辉,李天石..壳聚糖支架应用在组织工程中：组成复合支架及改性支架的前景[J].中国组织工程研究,2014,(52):8498-8503,6.基金项目
Funding:the Natural Science Foundation of Guangdong Province, No. S2013010012641 （）
