摘要
Abstract
BACKGROUND:The Chinese Clinicaltrial Register publishes the study design information and internationaly harmonized registration number, reviews study design, and randomly assigns in order to protect the quality of registration. OBJECTIVE:To analyze the current situation of stem cels and stem cel therapy for diabetes melitus in Chinese Clinical Trial Registry. METHODS: We searched the Chinese Clinical Trial Register (2008-2014) for stem cel research, and summarized these studies from the aspects of type of disease, study type, registration date, registration units, geographical distribution. Then, clinical trials about stem cels in the Chinese Clinical Trial Register were further analyzed. RESULTS AND CONCLUSION: There are 82 studies about stem cels, which mainly focus on blood disorders (32/39.0%), neurological disorders (20/24.4%), liver (9/11.0%), diabetes (5/6.1%). The registration date is mainly in 2012, and the main registration units are General Hospital of Armed Police Forces, Peking University People’s Hospital and the First Affiliated Hospital of Zhejiang University, which are mainly in Beijing and Zhejiang Province.
<br> There are five clinical trials about stem cel therapy for diabetes melitus, which are umbilical cord mesenchymal stem cel transplantation for diabetes from the General Hospital of Armed Police Forces, therapeutic efficacy and safety of mesenchymal stem cel transplantation for diabetes from Xinqiao Hospital, and autologous bone marrow stem cel transplantation for the treatment of diabetes from the 452nd Hospital of Chinese PLA. There are no enough trails about stem cels and stem cel therapy for diabetes in the Chinese Clinical Trial Register, and to improve clinical trial registration number and specification is the future direction of development.关键词
干细胞/移植/中国临床试验注册中心/检索分析/糖尿病/血液病/神经系统疾病/肝病/胚胎干细胞/骨髓干细胞/脐血间充质干细胞Key words
Subject headings：Stem Cels/Mesenchymal Stem Cels/Embryonic Stem Cels/Cord Blood Stem Cel Transplantation/Diabetes Melitus分类
医药卫生
