摘要
Abstract
BACKGROUND:Bone grafting is a commonly used method for treatment of limb comminuted fractures, including alogenic bone transplantation and autologous bone grafting, both of which have their own merit and demerit. OBJECTIVE:To explore the clinical effect of bone alograft and autograft in repairing limb comminuted fractures from the aspects of bone healing and bone activity. METHODS:A retrospective analysis was performed on the clinical data of 49 cases of limb fractures which were divided into control group (alogenic bone transplantation) and observation group (autologous bone grafting) according to treatment methods. Clinical healing time, bony union time, and bone specific alkaline phosphatase activity were observed and compared between the two groups. RESULTS AND CONCLUSION:The bone healing time and bony union time were (5.8±1.2) weeks and (5.8±1.5) months, respectively, in the observation group and (6.1±1.3) weeks and (6.1±0.8) months, respectively, in the control group, but there was no significant difference between the two groups (P > 0.05). The bone specific alkaline phosphatase activities were (10.45±1.53) μg/L in the observation group and (13.58±1.69) μg/L in the control group, and there was a marked difference between the two groups (P < 0.05). These findings indicate that both of alogenic bone transplantation and autologous bone grafting can achieve good results in the repair of limb comminuted fractures, but the autologous bone grafting has certain advantages in the promotion of bone healing ability.关键词
生物材料/骨生物材料/四肢骨折/粉碎性骨折/同种异体骨移植/自体骨移植Key words
Subject headings:Bone Transplantation/Fracture Healing/Fractures, Comminuted/Alkaline Phosphatase分类
医药卫生
