中国组织工程研究Issue(11)：1678-1682,5.DOI:10.3969/j.issn.2095-4344.2015.11.008
锥形束CT测量数据三维重建分析正畸牙槽嵴裂植骨修复单侧完全性唇腭裂的可行性
Orthodontic surgery with alveolar cleft grafting in patients with complete unilateral cleft lip and palate：a feasibility analysis based on cone-beam CT three-dimensional reconstruction
摘要
Abstract
BACKGROUND:Some cleft lip and palate patients at 9-10 years of age (the canine root development about 1/2-2/3) cannot achieve a good orthodontic outcome after bone grafting, and moreover, there is no unified therapeutic procedure for patients at 7-10 years of age before and after bone grafting. Cone-beam CT can reflect the fine structure accurately under the premise not to destroy normal tissue structure, and have access to the relevant measurement data by matched computer software. OBJECTIVE:To compare the therapeutic effect of orthodontic surgery combined with alveolar cleft bone grafting at different order for treatment of complete unilateral cleft lip and palate. METHODS: Sixty patients with complete unilateral cleft lip and palate admitted at Cangzhou People’s Hospital from 2012 to 2013 were enroled and divided into three groups with 20 in each group: group A, autologous iliac <br> graft was done folowed by 3 months of wearing orthodontic retainer; Group B, autologous iliac graft was done immediately after orthodontic treatment and then, orthodontic retainer was used for 3 consecutive months; group C, orthodontic retainer was used for 3 consecutive months folowing orthodontic treatment, and then, autologous iliac graft was performed folowed by another 3 consecutive months of wearing orthodontic retainer. RESULTS AND CONCLUSION:There were significant differences between groups A and C in terms of SNA, SNB, ANB, U1-NA and L1-NB (P < 0.01). Group B was significantly higher than the group A in SNB and L1/NB (P < 0.05). Compared with the group B, the SNB and U1/NA were reduced, while the SNA and L1/NB were increased significantly in the group C (P < 0.05). These findings indicate that for complete unilateral cleft lip and palate patients, the orthodontic treatment before and after bone grafting is better than simple pre- or post-grafting orthodontic treatment, which is conductive to the stability of corrected maxila.关键词
组织构建/组织工程/单侧完全性唇腭裂/单侧牙槽嵴裂/锥形束CT/三维测量/颅面形态/正畸矫治/牙槽嵴植骨/稳定性Key words
Cleft Palate/Cleft Lip/Alveolar Process/Bone Transplantation分类
医药卫生引用本文复制引用
沈悦,马海英,张彦升,王娟,时炳正..锥形束CT测量数据三维重建分析正畸牙槽嵴裂植骨修复单侧完全性唇腭裂的可行性[J].中国组织工程研究,2015,(11):1678-1682,5.基金项目
河北省科技支撑计划项目(1213078ZD) （1213078ZD）
