中国组织工程研究Issue(14)：2278-2282,5.DOI:10.3969/j.issn.2095-4344.2015.14.025
毛囊干细胞在皮肤伤口修复中的促进作用
Hair follicle stem cells promote the healing of skin wound
摘要
Abstract
BACKGROUND:Hair fol icle stem cel s derived from skin and hair have the most readily available sources, and cannot lead to serious complications and immunogenicity after col ection, which can be used for autologous transplantation. OBJECTIVE:To provide effective experiment basis for hair fol icle stem cel s in the repair of skin wound through reviewing the role of hair fol icle stem cel s in promote the repair of skin wound. METHODS:Articles related to hair fol icle stem cel s for the repair of skin wound were retrieved in CNKI and PubMed databases (1999-01/2014-12). The key words were“hair fol icle stem cel , skin repairing, regenerative medicine, tissue engineering”in Chinese and English, respectively. A total of 45 articles based on inclusion criteria and exclusion criteria were obtained for the review. RESULTS AND CONCLUSION:Hair fol icle stem cel s belong to adult stem cel s, which are easy to access, have a significant number, and possess differentiation potential and safety. Hair fol icle stem cel s can promote the repair of skin wound and provides good seed cel s for regenerative medicine and tissue engineering research through early vascularization of the skin, epidermal and appendage regeneration, signaling pathways, and transcription factors.关键词
干细胞/培养/毛囊干细胞/皮肤修复/早期血管化/信号通路/转录因子/再生医学/组织工程Key words
Hair Follicle/Stem Cells/Wound Healing/Transcription Factors分类
医药卫生引用本文复制引用
杜伟斌,全仁夫,郑宣,王拓..毛囊干细胞在皮肤伤口修复中的促进作用[J].中国组织工程研究,2015,(14):2278-2282,5.基金项目
浙江省科技厅公益技术应用研究社会发展项目(2010C330133)；杭州市萧山区社会发展重大科技攻关项目(2014205)@@@@the Public Benefit Technology Application Project for Social Development of Science and Technology Department of Zhejiang Province, No.2010C330133 （2010C330133）
the Social Developmental Project of Xiaoshan District of Hangzhou, No.2014205 （）
