中国组织工程研究Issue(15)：2431-2435,5.DOI:10.3969/j.issn.2095-4344.2015.15.026
灸法对肠易激综合征慢性内脏痛镇痛效应的研究与展望
Moxibustion therapy for chronic abdominal pain due to irritable bowel syndrome
摘要
Abstract
BACKGROUND:Chronic visceral pain is one of major complaints of irritable bowel syndrome which seriously affects patient’s quality of life. Recent researches have shown that moxibustion therapy has positive effects on aleviating chronic visceral pain in irritable bowel syndrome patients. <br> OBJECTIVE: To study the clinical utility of moxibustion in coping with chronic visceral pain of irritable bowel syndrome patients, and shed light on the theoretical basis of moxibustion analgesia, thereby to give insights into the further research and application on moxibustion. <br> METHODS: With the key words of “moxibustion, irritable bowel syndrome, visceral pain, abdominal pain” in Chinese and in English, respectively, a computer-based search was performed in CNKI, VIP, Wanfang and PubMed databases for articles published from January 1990 to October 2014. After the initial screening, the remained articles went through further selection and categorization. <br> RESULTS AND CONCLUSION:The result shows promising results of moxibustion on relieving chronic visceral pain for both two subtypes of irritable bowel syndrome patients, diarrhea type and constipation type. Moxibustion may exert an analgesic effect on chronic visceral pain in irritable bowel syndrome patients through regulation of visceral hypersensitivity, gastrointestinal motility disorders, brain-gut axis and neuroendocrine system disorders, immune dysfunction and low-grade inflammation in the gut, psychological abnormalities, and alteration of intestinal flora. However, to fuly understand the analgesia effect of moxibustion and elucidate its mechanism, more standardized randomized controled trials employing advanced scientific techniques and equipments wil stil be needed in the future.关键词
组织构建/组织工程/灸法/肠易激综合征/内脏痛/慢性痛/镇痛/效应/国家自然科学基金Key words
Subject headings：Irritable Bowel Syndrome/Abdominal Pain/Moxibustion/Analgesia分类
医药卫生引用本文复制引用
包春辉,吴焕淦,黄任佳,王硕硕,周志刚,胡智海,赵继梦,王思瑶,谭琳蓥,刘世敏..灸法对肠易激综合征慢性内脏痛镇痛效应的研究与展望[J].中国组织工程研究,2015,(15):2431-2435,5.基金项目
国家重点基础研究发展计划(973计划)项目资助(2015CB554501)，国家自然科学基金青年基金项目资助(81202752)，上海市青年科技英才扬帆计划项目资助(15YF1411200)Funding：the National Basic Research Program of China (973 Program), No.2015CB554501 （973计划）
the National Natural Science Foundation of China for the Youth, No.81202752 （）
Shanghai Sailing Program, No.15YF1411200 （）
