中国组织工程研究2015，Vol.19Issue(20)：3253-3257,5.DOI:10.3969/j.issn.2095-4344.2015.20.026
瘢痕:评估、防治、早期干预方法的研究与进展
Advances in scar prevention, early intervention and clinical assessment
摘要
Abstract
BACKGROUND:Potential mechanisms of scar formation and scar prevention strategies have become more important in current medical research. Scar assessment scales have the potential to contribute to better evaluation of scar properties in both research and clinical diagnosis. OBJECTIVE: To summarize the literatures addressing scar prevention and clinical assessment. METHODS: A computer search of CNKI database from 2000 to 2014, PubMed database from 1975 to 2014 and Foreign Medical Journal Ful-Text Service Database from 2000 to 2014 was performed using the keywords of "scar, prevention, treat, cicatrix, assessment, measure" in Chinese and English to retrieve articles related to scar prevention strategies and scar assessment scales. Totaly 39 articles meeting the inclusive criteria were included in result analysis. RESULTS AND CONCLUSION: During wound healing, the unbalance between colagen anabolism and katabolism can lead to the formation of pathological scar. Prevention and treatment of pathological scars should be combined, and early intervention was used in wound healing. General scar assessment scales include Vancouver Scar Scale, Visual Analog Scale, Patient and Observer Scar Assessment Scale, Manchester Scar Assessment Scale, Stony Brook Scar Assessment Scale, al of which have the potential to contribute to better evaluation of scar properties in both research and clinical diagnosis.关键词
组织构建/组织工程/瘢痕分类/瘢痕防治/瘢痕评估/量表/国家自然科学基金分类
医药卫生引用本文复制引用
马林枭,鲍济洪,陈斌..瘢痕:评估、防治、早期干预方法的研究与进展[J].中国组织工程研究,2015,19(20):3253-3257,5.基金项目
国家自然科学基金(81160238) （81160238）
云南省科技计划项目联合专项(2011FB189)资助 （2011FB189）
