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亚低温疗法对脑外伤患者细胞炎症因子的影响

赵湛元

中国实用神经疾病杂志Issue(11):18-20,3.
中国实用神经疾病杂志Issue(11):18-20,3.

亚低温疗法对脑外伤患者细胞炎症因子的影响

Influence of hypothermia treatment on inflammatory cytokines in patients with cerebral trauma

赵湛元1

作者信息

  • 1. 广东中山市人民医院外科ICU 中山 528403
  • 折叠

摘要

Abstract

Objective To explore the protective effect of hypothermia treatment on patients with cerebral trauma ,and ana-lyze its influence on inflammatory cytokines.Methods One hundred and twelve patients with cerebral trauma were divided into control group and hypothermia group.The patients of control group were given conventional therapy ,and patients of hypother-mia group were given hypotherima treatment.The effects of two groups were analyzed.Results Compared with those of control group ,the levels of IL-6 and TNF-αof hypothermia group were significantly decreased (P<0.05).The total effective rate of the hypothermia group was significantly higher than that of the control group (91.07% vs 76.79% ,P<0.05).The intracranial pressure of hypothermia group were significantly decreased in 24 ,48 and 72 h than that of the control group (P<0.05).The functional score of language and movement of the hypothermia group was significantly higher than that of the control group (75.00% vs 57.14% ,P<0.05).Conclusion The hypothermia treatment can reduce the level of inflammatory cytokines ,the intracranial pressure and temperature ,and improve prognosis of patients with cerebral trauma.

关键词

脑外伤/亚低温疗法/炎症因子

Key words

Brain injury/Hypothermai treatment/Inflammatory cytokines

分类

医药卫生

引用本文复制引用

赵湛元..亚低温疗法对脑外伤患者细胞炎症因子的影响[J].中国实用神经疾病杂志,2014,(11):18-20,3.

基金项目

2013年中山市科技计划项目 ()

中国实用神经疾病杂志

1673-5110

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