中国实用神经疾病杂志Issue(11)：48-50,3.
微创联合依达拉奉对高血压脑出血患者 MMP-9的影响及疗效观察
Influence of minimally invasive combined edaravone on MMP-9 of hypertensive patients with cerebral hemor-rhage and its curative effect
苏彦果 1袁发东 2李建明 1贾婕 1高钟生1
作者信息
- 1. 河北张家口市第一医院神经内科 张家口 075000
- 2. 河北康保县人民医院内科 康保 076650
- 折叠
摘要
Abstract
Objective To observe the minimally invasive combined edaravone on the serum of patients with hypertensive cerebral hemorrhage matrix metalloproteinase-9 (MMP-9) impact.Methods A retrospective analysis of 80 cases of cerebral hemorrhage patients in our hospital from January 2011-2013 in December ,who were randomly divided into observation group and control group ,40 cases in each group ,the control group was given conventional treatment ,the observation group was ob-served in the conventional treatment group based on the use of edaravone ,continued drug were used for about 2 weeks ,the ser-um levels of MMP-9 ,and recorded the NIHSS score and BI index were detected.Results Serum MMP-9 levels before treat-ment showed no significant difference (P> 0.05) ,and significant differences after treatment (t= 11.2636 , P< 0.01).The difference between the two groups before treatment and BI ,MESSS was not statistically significant (all P>0.05) ,and BI con-tent MESSS significant difference after treatment in both groups (respective t=3.1762 ,3.9890 ,all P<0.01).Conclusion Min-imally invasive and edaravone on MMP-9 in patients with hypertensive intracerebral hemorrhage are mainly for inhibition , which can effectively reduce the patients 'inflammatory response after cerebral hemorrhage ,protect brain cells function ,it is worthy of promotion and application.关键词
依达拉奉/高血压/脑出血/MMP-9Key words
Edaravone/Hypertension/Cerebral hemorrhage/MMP-9分类
医药卫生引用本文复制引用
苏彦果,袁发东,李建明,贾婕,高钟生..微创联合依达拉奉对高血压脑出血患者 MMP-9的影响及疗效观察[J].中国实用神经疾病杂志,2014,(11):48-50,3.
